See London like never before! A fantastic flat course route on closed roads passing by some of the city’s most iconic landmarks, including Nelson’s Column, The London Eye and Big Ben.

Fampridine (Fampyra) is a drug treatment which has been shown to improve walking speed for some adults with multiple sclerosis (MS). Fampridine is taken orally as tablets.

Join Team MS Trust for the Brighton Marathon and raise vital funds. Make a difference, one stride at a time. Register today!

Take on the Barcelona Marathon 2027 with MS Trust. Run through Barcelona’s scenic landmarks and raise vital funds to support those affected by MS.

With no government funding, much of our vital support for people living with MS is only possible through gifts in wills. Help us make a difference.

Find out about the latest charity job opportunities at the MS Trust.

Our Advanced MS Champions programme funds specialists to provide guidance and coordinated care for some of the UK's 48,000 people with advanced MS. Find out how to apply here.

Do summer in style with a walk through some of London’s lesser-known historic areas, with 10km or 25km distance options and a marathon option for those seeking an unforgettable challenge! Walk as an individual, or as a team. Sign up today to make a real difference.

Ultra Challenge Series 2026