Cyclophosphamide is an immunosuppressive drug. In multiple sclerosis (MS), it acts to reduce the numbers of T and B cells that can trigger an immune attack.

Some people taking medication may make antibodies against that drug, reducing or neutralising the drug's effectiveness.

Fatigue is one of the most common symptoms of multiple sclerosis. MS fatigue is very different from the tiredness or exhaustion that people without MS may have and is out of all proportion to any activity you may have been doing.

Take the the streets of Paris, past iconic landmarks and cheering crowds. Start at the Arc de Triomphe, past the Lourve and finish with views of the Norte Dame and Eiffel Tower

We cover the latest research coming out of ECTRIMS 2025. We discuss study results on the impact of Ocrevus on maintaining hand and arm function; how MS affects women after the menopause; the links between ultra-processed foods and MS disease activity; myelin repair; and stopping DMTs in older people.

Some people with MS find that their symptoms get worse in the cold. Here's why that might happen and what you can do to manage cold sensitivity.

One woman shares her MRI scan experience, explaining what happens before, during and after an Magnetic Resonance Imaging scan.

Having an MRI scan is often a key part of your diagnosis process and may be used to monitor your treatment. We spoke to Dr Will Brown to find out what MRI scans can show us, and how they are used and interpreted in MS care.

The MS hug sounds quite nice – if you haven’t experienced it! We explain this uncomfortable multiple sclerosis symptom.