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Lesion (MS lesion)
An MS lesion is an area of damage or scarring in the brain or spinal cord. Lesions are caused by inflammation that results from the immune system attacking the myelin sheath around the nerves in your central nervous system.
Information - A-Z
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Lhermitte's sign
A sudden, electric shock-like feeling that passes down the back of the neck and can reach the fingers and toes. Find out more about Lhermitte's sign, why it happens and how to manage it.
Information - A-Z
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Life expectancy
Multiple sclerosis (MS) is not considered a terminal condition and long-term studies suggest that MS only has a small impact on life expectancy.
Information - A-Z
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Lipoic acid
Lipoic acid (also known as alpha lipoic acid) is being tested as a treatment for secondary and primary progressive multiple sclerosis (MS). It is taken as a tablet once daily.
Information - A-Z
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Low dose naltrexone (LDN)
Naltrexone (Nalorex) is a drug used to treat people with addictions. Following anecdotal reports that low doses help the symptoms of people with a wide range of conditions, there have been a few pilot studies of low dose naltrexone (LDN) in multiple sclerosis.
Information - A-Z
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Lumbar puncture for MS
A lumbar puncture is a diagnostic test for multiple sclerosis that involves removing and analysing a sample of cerebrospinal fluid (CSF), the fluid that surrounds the brain and spinal cord within the skull and backbone. It is sometimes referred to as a spinal tap.
Information - A-Z
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Magnetic resonance imaging (MRI)
Magnetic resonance imaging (MRI) is a scanning technique that produces images of slices through the body using magnetic fields and radio waves. MRI images of the brain and spinal cord can be used to diagnose MS.
Information - A-Z
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Masitinib (AB1010)
Masitinib is an experimental drug treatment for secondary and primary progressive MS. It is taken as a tablet, twice daily.
Information - A-Z
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Massage
Massage is used by some people for the relief of pain and musculoskeletal symptoms of multiple sclerosis. It can be relaxing and may help general well-being. Massage is often used in combination with aromatherapy.
Information - A-Z
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MS information & support
About MS
Newly diagnosed
Young people and MS
Living with advanced MS
Causes of MS
How common is multiple sclerosis?
Types of MS
What is MS?
Symptoms & diagnosis
Worried you have MS?
Signs and symptoms
How is MS diagnosed?
What's causing my symptoms?
MS relapses and their management
Drugs & treatments
How is MS treated?
Disease modifying therapies (DMTs)
DMTs approved for use in the UK
Compare disease modifying therapies (DMTs)
Drugs in development
Treatment finder
Non-drug therapies
Health & wellbeing
Thinking and memory problems
Staying Smart
Exercise
Diet and MS
Wellbeing
Family, care & money
Relationships and family life
Care and carers
Home and travel
Work, money and legal
Support & services
Contact our MS helpline
MS services near me
My MS expert
Order a free MS publication
Listen to our podcast
Join our Facebook group
Find support groups
A-Z of MS
Get involved
Donate
Make a donation
Make a regular donation
Donate in memory
Other ways to donate
Gift Aid
Fundraise
MS Trust Exclusives
Do it your way
Trekking and walking events
Running events
Cycling events
Daredevil events
Fundraise while you shop
Get your fundraising guide
Pay in your fundraising
Raise awareness
Bring Your MS to Work
World MS Day 2026
MS Awareness Week 2026
Volunteer
Leave a gift in your will
Corporate fundraising
Corporate giving
Payroll giving
Pharmaceutical and other industry supporters
News & stories
Latest news & stories
Keep up to date
Sign up for updates
Update your address
Send us your story
Research
Our research
For researchers
Our research leadership
Studies we support
For health professionals
Resources
Clinical learning
Professional development
Service development
Courses & training
Funding your learning
MS Trust conference
Development Module
Study days
External courses
Therapists in MS (TiMS)
About TiMS
Meet the TiMS working group
TiMS resources
TiMS newsletters
Join the TiMS network
Order publications
Latest
Latest news for HPs
Keep in touch
MS in Practice
Programmes
Advanced MS Champions programme
Case studies
MS Forward View
Shop