What is baclofen used for in MS?
How do I take baclofen?
Baclofen is taken by mouth (orally) as tablets or as a liquid. Treatment usually starts with a small dose that can be increased in steps until it is most effective or side effects become a problem.
It’s recommended that you take the tablets with food or a milk drink to reduce the chance of experiencing nausea.
Speak to your MS team about the best time to take baclofen. Some people take it just before bed to help with spasticity and spasms during the night. Other people take it about an hour before doing certain activities (e.g. showering or getting out of bed) to make them easier.
If you have more advanced spasticity, a smaller dose of the drug can be given directly into the spine (intrathecally) using an implanted pump – this is known as intrathecal baclofen.
What side effects could I get with baclofen?
If the dose is too high, muscles can become weak so it’s important to get the balance right between reducing stiffness and not reducing strength in your muscles.
Stopping treatment suddenly may cause severe withdrawal symptoms. These can include hallucinations and seizures. You should talk to your doctor before stopping treatment, and plan a gradual reduction of the daily dose.
How does baclofen work?
Baclofen is a muscle relaxant. It works by reducing the transmission of messages between nerve cells so muscles are less likely to contract and become stiff.
Ask the expert: spasticity and spasms
Spasticity and spasms are a common symptom of MS and can have a big impact on your daily life. To find out how they can be successfully treated and managed, we put some of your questions to physiotherapist, Katrina Buchanan.
Baclofen is used in MS to reduce muscle stiffness and spasms. It is usually taken as a tablet, but some people find the tablets aren't effective. Baclofen may be delivered intrathecally instead, via the spine. Find out more in this A-Z entry.
Spasticity and spasms
Spasticity is a symptom of MS where the muscles feel stiff, heavy and difficult to move. A spasm is a sudden stiffening of a muscle.